Recent Relevant Publications

  • Essentials of Glycobiology, 2nd Edition, Edited by Varki, A., Cummings, R., Esko, J.D., Freeze, H.H., Stanley, P. ,Bertozzi, C., Hart, G.W., and Etzler, M.E. Cold Spring Harbor Laboratory Press, New York, 2008
  • *MacArthur, J.M., Bishop, J.R., Wang, L., *Stanford, K.I., Bensadoun, A., Witztum, J.L., and Esko, J.D. (2007) Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members. J. Clin. Invest. 117:153-164. Commentary: Mahley, R.W. and Huang, Y. (2007) J. Clin. Invest. 117:94-98
  • Pallerla,S.R., Pan, Y., Zhang, X., Esko, J.D., and Grobe, K. (2007) Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development. Dev. Dyn. 236:556-563.
  • Pönighaus, C., Ambrosius, M., Carrera-Casanova, J., Prante, C., Kuhn, J., Esko, J.D., Kleesiek, K., Götting, C. (2007) Human xylosyltransferase II is involved in the biosynthesis of the uniform tetrasaccharide linkage region in chondroitin sulphate and heparan sulphate proteoglycans. J. Biol. Chem. 282:5201-5206.
  • *Elson-Schwab, L., *Garner, O.B.,* Schuksz, M., *Crawford, B.E., Esko, J.D., and Tor, Y.  (2007) Guanidinylated-Neomycin delivers large, bioactive cargo into cells through a heparan sulfate dependent pathway. J. Biol. Chem. 282:13585-13591.
  • Borsig, L., Wang, L., Cavalcante, M.C., Cardilo-Reis, L., Ferreira, P.L., Mourao, P.A., Esko, J.D., and Pavao, M.S. (2007) Selectin-blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea-cucumber: Effect on tumor metastasis and neutrophil recruitment. J. Biol. Chem. 282:14984-14989.
  • Fuster, M.M., Wang, L., Castagnola, J., Sikora, L., Reddi, K., Lee, P.H.A., Radek, K., Gallo, R.L., Sriramarao, P. and Esko, J.D. (2007) Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis. J. Cell Biol. 177:539-549.
  • Bode, L., Salvestrini, C., Park, P.W., Li, J.-P,  Esko, J.D., Murch, S., Freeze, H.H. (2007) Heparan sulfate and syndecan-1 are essential in maintaining intestinal epithelial barrier function. J. Clin. Invest. 118:229-238.
  • Bishop, J.R., *Schuksz, M., and Esko, J.D. (2007), Heparan sulfate proteoglycans fine-tune mammalian physiology.  Nature 446:1030-1037
  • Coppi, A., Tewari, R., Bishop, J.R., Bennett, B.L., Lawrence, R., Esko, J.D., Billker, O. and Sinnis, P. (2007) Heparan sulfate proteoglycans provide a signal to plasmodium sporozoites to stop migrating and productively invade cells. Cell Host Microbe 2:316-327. Commentary: Miguel Prudéncio, M. and Mota, M.M. (2007) To migrate or to invade: those are the options. Cell Host Microbe 2:286-288.
  • Pan, Y., Carbed, C., Powers, A., Esko, J.D., Grobe, K., Feng, G.-S. and Zhang, X. (2007) Bud specific N-sulfation of heparan sulfate regulates Shp2 dependent FGF signaling during lacrimal gland induction. Development, 135:301-10.
  • Brown, J.R., Crawford, B.E., and Esko, J.D. (2007) Glycans: A fount for drug discovery. Crit. Rev. Biochem. Mol. Biol. 42:481 - 515. 
  • Lawrence, R., Lu, H., Rosenberg, R.D., Esko, J.D., Zhang, L. (2008) Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans. Nat. Methods. 5:291-292
  • Pallerla, S.R., Lawrence, R., Lewejohann, L., Pan, Y., Fischer, T., Schlomann, U., Zhang, X., Esko, J.D., Grobe, K. (2008) Altered heparan sulfate structure in mice with deleted NDST3 gene function. J. Biol. Chem. 283:16885-16894
  • *Garner, O.B., Yamaguchi, Y., Esko, J.D., and Videm, V. (2008) Small changes in lymphocyte development and activation in mice through tissue-specific alteration of heparan sulphate. Immunology 125:420-429.
  • *Schuksz, M., Fuster, M.M., Brown, J.R., *Crawford, B.E., Ditto, D.P., Lawrence, R., Glass, C.A., Wang, L., Tor, Y., and Esko, J.D. (2008) Surfen, a small molecule antagonist of heparan sulfate. Proc. Natl. Acad. Sci. 105:13075-13080.
  • Lawrence, R., *Olson, S.K., Steele, R.E., Wang, L., Zhang, L., Warrior, R., Cummings, R.D. and Esko, J.D. (2008) Evolutionary differences in glycosaminoglycan fine structure detected by quantitative glycan reductive isotope labels. J. Biol. Chem. 283:33674-33684. PMID: 18818196 PMC2586254
  • Weinstein, M.M., Beigneux, A.P., Davies, B.S., Gin, P., Yin, L., Estrada, K., Melford, K., Bishop, J.R., Esko, J.D., Fong, L.G., Bensadoun, A., Young, S.G. (2008) Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice. J. Biol. Chem. 283:34511-34518. PMID: 18845532 PMC2596386
  • *Meissen, J.K., Sweeney, M.D., Girardi, M., Lawrence, R., Esko, J.D., Leary, J.A. (2009) Differentiation of 3-O-Sulfated Heparin Disaccharide Isomers: Identification of Structural Aspects of the Heparin CCL2 Binding Motif. J. Am. Soc. Mass Spectrom. 20:652-657. PMID: 19185514
  • Bakker, H. Oka, T. Ashikov, A., Yadav, A., Berger, M., Rana, N.A., Bai, X., Jigami, Y., Haltiwanger, R.S., Esko, J.D., and Gerardy-Schahn, R. (2009) Functional UDP-xylose transport across the ER/Golgi membrane in a Chinese hamster ovary cell mutant defective in UDP-xylose synthase.   J. Biol. Chem. 284:2576-2583 PMID: 19028698
  • Brown, J.R., Yang. F., Sinha, A., Ramakrishnan, B., Tor, Y., Qasba, P.K., and Esko, J.D. (2009) Deoxygenated disaccharide analogs as specific inhibitors of b1-4 galactosyltransferase 1 and selectin-mediated tumor metastasis. J. Biol. Chem. 284:4952-4959 PMID: 19106107
  • Bishop, J.R., *Stanford, K.I. and Esko, J.D. (2008) Heparan sulfate proteoglycans and triglyceride-rich lipoprotein metabolism. Curr. Opin. Lipidol. 19:307-313. 

* indicates graduate students